A
postdoctoral position is available from April 1, 2010 at the University
of Oxford to study the structure, function, and small-molecule
antagonism of ion channels that are of high medical relevance. The
candidate will join the laboratory of Dr. Jason Schnell, and be
responsible for the development and structural analysis of ion channel
systems by high-resolution solution NMR. The main approach will be to
use the tools of biophysics (e.g. NMR, fluorescence, and
ultracentrifugation) and molecular biology in combination with
functional assays (e.g. liposomal ion flux assays) to elucidate the
molecular details of activity.
The University of Oxford provides abundant resources
for the production and characterization of proteins, including access
to NMR spectrometers operating at 500 to 950 MHz. The lab is located in
a new building designed to promote collegiality and scientific
collaborations:
http://www.nature.com/nature/journal/v457/n7229/full/457541a.html
Funding for the position is provided by the Medical
Research Council for 1 year in the first instance, with the possibility
for extension.
Please check the following website for
qualifications and application instructions:
http://www.bioch.ox.ac.uk/aspsite/index.asp?sectionid=vacancies
For informal queries about the lab and research
projects, please contact Jason Schnell by e-mail: jason.schnell@bioch.ox.ac.uk
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