Postdoctoral Position in Enzyme Dynamics by Biomolecular NMR

    A postdoctoral position, funded primarily by an NSF grant, is available immediately to study internal motions and domain rotations coupled to the catalytic cycle of a 51 kD enzyme important in bacterial virulence. Hypotheses of selected fit and coupling to the intermediate bound will be tested. Preference will be given to candidates with published experience in biomolecular NMR. Experience and interests in enzymology, molecular biophysics, and protein preparative work are also welcome. The project is poised for rewarding progress by the availability of virtually complete backbone assignments of the 463-residue phosphomannomutase, intriguing results on the ligand binding, enzymology and structural changes, and the high performance of the Bruker 800 MHz Avance III NMR spectrometer with TCI cryoprobe. The stimulating academic environment at the University of Missouri includes broad faculty, postdoctoral, and PhD student expertise in structural biology and biophysics. The department’s website is: http://www.biochem.missouri.edu/ 

    Send inquiries, applications, and two to three letters of recommendation to

Professors Steve Van Doren and Lesa Beamer at vandorens@missouri.edu and beamerl@missouri.edu

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117 Schweitzer Hall, Biochemistry Dept., Univ. of Missouri,
Columbia, MO  65211
USA
FAX: 1 (573) 882-5635